Hollyoaks is set for havoc with a new serial killer dubbed the Angel of Death striking victims in the local hospital.

The murderer will strike first in January 2015 – killing off a main cast member with a second popular character narrowly escaping with their life, the Daily Star revealed.

The serial killer is to be known as the Angel of Death as they will attack the weak and vulnerable in hospital, with multiple victims.

Hollyoaks hospital
The hospital will play host to a serial killer (Lime Pictures)

And the identity of the murderer is being kept so top secret by writers that even the actor who plays them is yet to be told who they are.

Though soap bosses haven’t decided how many people will be killed off, the Angel of Death is set to carry out his or her work throughout 2015, and they will not be unmasked for months.

Hollyoaks bosses have even built a new hospital set for the Angel of Death to roam.

Jennifer Metcalfe as Mercedes McQueen
Mercedes McQueen (Jennifer Metcalfe) is set to leave the soap (Lime Pictures)

Meanwhile, the McQueen family are to be left devastated when a train crash kills off one of their clan later this month. And a second character will also die in the accident, which will feature a real train bought by soap bosses for the stunt.

Jennifer Metcalfe and Gemma Merna, who play McQueen sisters Mercedes and Carmel, are getting ready to leave the Channel 4 soap, so one of their characters is rumoured to be at the centre of the tragedy.